NIH Grant Awarded for Multiple Sclerosis Research

Professors Jennifer McDonough (PI) and Ernie Freeman (PI) (Department of Biological Sciences) together with Professor Roger Gregory (co-PI) (Department of Chemistry and Biochemistry) have been awarded a two-year, $398,682 grant from the National Institutes of Health to support their project “Neuronal Expression of Hemoglobin in Multiple Sclerosis Cortex.”

Hemoglobin is a protein that transports oxygen in the blood, but surprisingly, it is also expressed by neurons and may be involved in neuronal respiration. Recent work by the research group at Kent found that hemoglobin expression is increased in multiple sclerosis brain tissue compared with controls [Broadwater et al, Biochimica et Biophysica Acta, 1812 (2011) 630–641]. The goal of this NIH funded research is to understand the regulation and function of hemoglobin expression in neurons, as well as the distribution and extent of hemoglobin expression in the brain and its significance to the neuropathology of multiple sclerosis.

  • Dr. Roger Gregory
    Dr. Roger Gregory
  • Hemoglobin
    Hemoglobin expression in multiple sclerosis postmortem brain tissue detected by immunofluorescent staining with antibodies to hemoglobin (red) and neurofilament (green).
POSTED: Saturday, September 29, 2012 04:34 PM
UPDATED: Saturday, December 03, 2022 01:02 AM

Student-athletes balance a demanding mix of pressures. Practices and games fill their schedules. Coursework competes for time. Social media puts their performances and their mistakes on display.

Now, researchers at are studying whether a smartphone app, called , can help student-athletes manage that stress and perform better because of it.

Several faculty members from ’s College of Arts and Sciences, along with community partners, are among the recipients of the 2026 Engagement Awards from the Community Engaged Research Institute (CERI).

and the City of Cleveland have launched a new research and training initiative aimed at strengthening trust, collaboration and accountability between the Cleveland Division of Police and city residents. The project is supported by a $20,000 grant from ’s Community Engaged Research Institute.